Unusual Uses of Common Drugs 2015 pdf
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Unusual uses of common drugs By PHARMACIST : Ahmed Mohammed Yossef
Pages: 216
- Language: English
- Format: PDF
- Size : 4.40 MB
Contents :
. Acetyl salicylic acid
. Amitriptyline
. Betamethasone
. Bromocriptine
. Bupropion
. Calcium
. Cabergoline
. Combined oral contraceptive
. Dexamethasone and betamethasone
. Diltiazem
. Domperidone
. Erythromycin
. Finasteride
. Folic acid
. Gonadotropins
. Insulin
. Liraglutide
. MegestrolAcetate
. Metformin
. Metronidazole
. Nifedipine
. Prednisolone
. Propranolol
. Sildenafil
. Sodium bicarbonate
. Spironolactone
. Sulfasalazine
. Tadalafi
. Topiramate
. Trimethoprim-Sulfamethoxazole
. Vitamin D
PREFACE
Unusual uses of common drugs is a new vision to experience the hidden side in medications effect.
It is the indications that health care provider not used to deal with it. Some indications may be approved by FDA other indications may be not yet approved.
Unusual uses of common drugs differ from off-label uses that some indications approved by FDA. health care provider awareness of these unusual indications leading to the best counselling to the patient and let him use these medications in best way, also give health care provider many choices in some critical cases.
Unusual uses of common drugs open the health care provider’s mind towards a new ways to the effect of medications.
A salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an antiinflammatory medication.
Aspirin also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream.
Pregnant women at high risk for preeclampsia should take low-dose aspirin (75mg81mg) every day after their first trimester .
Preeclampsia is a complex condition that occurs in pregnant women and involves an increase in blood pressure and excess protein in the urine after 20 weeks of pregnancy.
Daily low-dose aspirin in middle and late pregnancy can significantly reduce the occurrence of preeclampsia among these women and it can lower the risk of preterm birth or low birth weight resulting from the pregnancy-related condition because aspirin helps blood flow between the placenta and the fetus.
High or normal doses (>325 mg) block production of prostacyclin and thromboxane, and low-dose aspirin (60–83 mg) results in selective block of thromboxane production, and favors the prostacyclin (vasodilation) pathway. This provides the basis for the use of low-dose aspirin to forestall or prevent pregnancy-induced hypertension. Importantly, low-dose aspirin does
not completely inhibit thromboxane and does not completely ‘spare’ prostacyclin. One group of investigators found that 81 mg of aspirin inhibited thromboxane by 75 percent, but also inhibited prostacyclin by approximately 20 %.
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